Overview
Rapamycin (sirolimus) is an mTOR inhibitor FDA-approved for transplant immunosuppression. In longevity clinics, low-dose intermittent rapamycin (e.g., 2–6 mg weekly) is used off-label to target cellular aging pathways. Early animal data show lifespan extension, but human evidence remains limited. Careful screening is essential because rapamycin can suppress immunity, elevate lipids, and impair wound healing.
Common Reasons to Rapamycin
- Biohackers or aging-focused patients exploring mTOR modulation
- Individuals with metabolic or inflammatory concerns hoping to slow biological aging
- Patients already on NAD+, metformin, or GLP-1 programs seeking synergistic therapy
When to seek treatment: Only after thorough medical evaluation and baseline labs. In-person care is required for active infection, recent surgery, uncontrolled diabetes, pregnancy, cancer treatment, or immunodeficiency.